NFIX – one gene, two knockouts, multiple effects
نویسندگان
چکیده
A previous knockout of the transcription factor gene nuclear factor IX (NFIX) in mice produced impaired development of the corpus callosum and severe skeletal defects. A recent paper in BMC Developmental Biology reports an apparently similar NFIX knockout that produced marked differences in phenotype, raising intriguing general questions about the possible causes of such differences in mouse knockouts.
منابع مشابه
A DNA Sequence Directed Mutual Transcription Regulation of HSF1 and NFIX Involves Novel Heat Sensitive Protein Interactions
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عنوان ژورنال:
- Journal of Biology
دوره 7 شماره
صفحات -
تاریخ انتشار 2008